Why is Doxycycline Hyclate preferred for eperythrocytosis?
According to the data, it was originally classified as a member of the Microsporidia family (1974) due to the inconsistency of its biological characteristics with other conventional bacteria. Later classified as rickettsite. However, it is not an intracellular obligate parasite, it is small, has no cell wall, and is highly resistant but sensitive to tetracycline. Later, after sequencing, it was found that the genetic sequence of the pathogen was very similar to that of Rickettsia, but it was closer to the sequence of Mycoplasma. Therefore, in the process of treating eperythrozoonosis with tetracyclines, we found that doxycycline hydrochloride in tetracyclines had the best effect.
The main reasons for the better effect of doxycycline hydrochloride in the treatment of trachea and bronchitis in livestock and poultry are:
⑴ wide antibacterial spectrum, strong antibacterial effect. In addition to its good effect on Gram-positive bacteria and Gram-negative bacteria, it can inhibit respiratory Mycoplasma, Rickettsia and other pathogens that are resistant or insensitive to other drugs.
(2) Doxycycline hyclate is absorbed quickly after oral administration, it can exert its maximum effect in about 3 hours, and maintain its effect in the body for a long time.
(3) Doxycycline hyclate has certain antitussive, expectorant and asthmatic effects. These effects have been confirmed by animal experiments and are features that other antibiotics do not have.
These unique advantages of the above-mentioned doxycycline hyclate, as well as the plasma concentration of doxycycline hydrochloride that maintains an effective effect in livestock and poultry are longer than those of the commonly used clinical respiratory drugs. Therefore, it has better curative effect in the treatment of livestock and poultry trachea and bronchi.
