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Avermectin
CAS No.
Appearance
Purity
Molecular Formula
Molecular Weight
Solubility
Synonyms
Table of Contents
Overview
Avermectin (CAS 65195-55-3) is a naturally derived macrocyclic lactone obtained from the controlled fermentation of Streptomyces avermitilis. It contains mainly Avermectin B1a and B1b, supplied as a white to light yellow crystalline powder with stable chemical and physical characteristics.
As a fermentation-based veterinary active ingredient, Avermectin is widely used by manufacturers in the development of multiple formulation types such as premixes, oral preparations, topical solutions, and other solid or liquid forms. Its reliable activity profile and compatibility with common excipients support broad applicability in veterinary pharmaceutical production.
We supply export-grade Avermectin with consistent assay, impurity control, and particle characteristics to meet manufacturing requirements in different processing environments.
Product Information
| Product Name | Avermectin |
| CAS No. | 65195-55-3 |
| Source | Fermentation product of Streptomyces avermitilis |
| Appearance | White to light yellow crystalline powder |
| Solubility | Practically insoluble in water; soluble in methanol, ethanol, and chloroform |
| Assay (HPLC) | Not less than 95.0% (sum of B1a and B1b) |
| B1a / B1b Ratio | ≥80:20 |
| Loss on Drying | ≤2.0% |
| Residue on Ignition | ≤0.1% |
| Heavy Metals | ≤10 ppm |
| Packaging | 1 kg aluminum foil bag or 25 kg fiber drum |
| Storage | Store tightly closed, protected from moisture and light |
| Shelf Life | 24 months under recommended conditions |
Technical Specifications
| Form | Crystalline powder |
| Color | White to light yellow |
| Purity (HPLC) | ≥95.0% |
| B1a Content | ≥80% |
| B1b Content | ≤20% |
| Water Content | ≤2.0% |
| Residue on Ignition | ≤0.1% |
| Heavy Metals | ≤10 ppm |
Quality Assurance
Each batch of Avermectin is tested according to internal quality specifications to ensure reliable assay, impurity limits, and physical characteristics suitable for veterinary API manufacturing.
- Analytical testing includes HPLC assay, identity verification, and impurity profiling.
- Batch-to-batch stability is monitored to support consistent performance in formulation use.
- Packaging and labeling can be customized based on handling requirements.
- Samples for evaluation can be arranged before commercial orders.
Applications
- Formulation versatility: Avermectin is commonly used by manufacturers for producing premixes, oral solid forms, topical preparations, and other veterinary pharmaceutical formats.
- Fermentation-based activity: Its naturally derived macrocyclic lactone structure offers a consistent activity profile valued in many veterinary formulation processes.
- Compatibility: Suitable for blending, granulation, and dissolution with standard excipients used in veterinary API handling.
- Process behavior: The powder provides stable handling performance, supporting uniformity during mixing and downstream processing.
- Industry usage: Frequently selected in production lines that require fermentation-origin active ingredients with controlled impurity levels.
Product FAQ
What is Avermectin used for in manufacturing?
Avermectin is used by veterinary pharmaceutical manufacturers as an active ingredient in the production of various solid and liquid formulations.
What is the difference between Avermectin and its derivatives?
Avermectin represents the original fermentation-based compound group. Its derivatives, such as semi-synthetic variants, are developed for different formulation needs or stability requirements.
Why is Avermectin supplied as a mixture of B1a and B1b?
The natural fermentation process produces Avermectin as a mixture of B1a and B1b, and this ratio is important for ensuring consistent quality and performance.
What information is useful when requesting a quotation?
It is helpful to specify the required quantity, packaging preference, expected delivery location, and any technical parameters important to your production line.
Q1. How can I request a quotation or sample?
You can click the “Send Inquiry” button on this page or email us directly at [email protected].
Samples are available for most products, and our sales team will reply within 24 hours with detailed pricing and documentation .
Q2. What is the minimum order quantity (MOQ)?
The MOQ is 0.5 kg for most products.
For laboratory evaluation or small trial batches, smaller quantities can be arranged depending on stock availability.
Q3. What certifications do your products comply with?
Our GMP-certified partners operate under ISO, CEP, and FSC standards.
Each batch is supplied with a full set of COA, MSDS, and export documents to ensure quality traceability.
Q4. How long does delivery take?
Usually 3–7 working days for available stock and 2–3 weeks for customized specifications or large orders.
Q5. Which payment methods do you accept?
We accept T/T, L/C, and other agreed terms depending on the order volume and region.
Q6. Can you provide contract manufacturing or custom formulation support?
Yes. We cooperate with multiple GMP facilities to offer custom synthesis, formulation, and registration support for specific markets.
Packaging Information
Standard packing: 25 kg fiber drum or 1 kg foil bag
Double PE inner liner for moisture protection
Custom packaging available on request
Storage & Stability
Store in a cool, dry environment away from direct light. Shelf life 24 months under recommended conditions.
Transportation
Shipped by air, sea, or express according to customer preference. Dangerous goods comply with IATA/IMDG standards if applicable.
Our company and partner facilities hold valid GMP and ISO certificates issued by national authorities, ensuring that every batch meets strict quality and traceability standards required for international veterinary API markets.
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