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Carbachol
CAS No.
Appearance
Purity
Molecular Formula
Molecular Weight
Solubility
Synonyms
Table of Contents
Overview
Carbachol is a synthetic cholinergic agonist used in pharmaceutical and veterinary formulations.
It is a hygroscopic crystalline powder that complies with both USP and EP pharmacopeial standards.
The product is primarily used for smooth-muscle stimulation, research applications, and regulated formulations requiring
high-purity Carbachol.
Product Information
Chemical Name: 2-(Carbamoyloxy)-N,N,N-trimethylethanaminium chloride
CAS No.: 51-83-2
Pharmacopeial Status: USP / EP compliant
Quality Range: USP: 99.0–101.0% (dried basis); EP: 99.0–101.5%
Appearance: White or almost white crystalline powder; hygroscopic
Solubility: Very soluble in water; sparingly soluble in ethanol (96%)
Storage: Store in airtight containers, protected from light
Applications: Cholinergic agonist, research reagent, pharmaceutical intermediate
Technical Specifications
| Identification | IR spectrum complies (USP/EP); positive reaction for chloride |
| Assay | USP: 99.0–101.0% (dried basis); EP: 99.0–101.5% |
| Appearance of Solution | Clear and colorless |
| Loss on Drying | USP: ≤2.0%; EP: ≤1.0% |
| Sulfated Ash | ≤0.1% |
| Melting Range | 200–204°C (with decomposition) |
| Related Substances | TLC: complies with EP / USP impurity limits |
| Solubility | Very soluble in water; sparingly soluble in ethanol |
| Storage | Airtight container; protect from light |
Quality Assurance
Our Carbachol is manufactured under GMP-compliant conditions and tested according to
USP and EP pharmacopeial monographs. Each batch undergoes:
- Full pharmacopeial assay verification
- IR identification according to USP/EP
- Related substances analysis (TLC per EP requirements)
- LOD, sulfated ash, and physical property testing
- COA, MSDS, and regulatory documentation support
Batch-specific COAs are available upon request.
Applications & Dosage
Carbachol is commonly applied in:
- Pharmaceutical formulations requiring cholinergic stimulation
- Veterinary research and regulated product development
- Laboratory assays involving muscarinic and nicotinic receptor activation
- Ophthalmic research applications
Note: Dosage depends on regulatory guidelines and application type.
This raw material is not intended for direct administration without formulation.
Product FAQ
Q1: What is Carbachol commonly used for?
Carbachol (CAS 51-83-2) is widely used as a cholinergic agonist in ophthalmic research, receptor-activation assays, and regulated pharmaceutical development. It serves as a raw material for formulations requiring controlled parasympathomimetic activity.
Q2: Is this compound an agonist or antagonist?
Carbachol is a direct-acting cholinergic agonist. It activates both muscarinic and nicotinic receptors, making it suitable for studies involving smooth-muscle stimulation and neurotransmitter response analysis.
Q3: How does this ingredient affect the pupils?
Carbachol induces miosis (pupil constriction) by stimulating muscarinic receptors in the iris sphincter muscle. This effect makes it a commonly referenced compound in ophthalmic physiological studies.
Q4: Why is Carbachol relevant in glaucoma-related research?
Carbachol is known to reduce intraocular pressure by enhancing aqueous humor outflow. Although supplied only as a raw material, its pharmacological properties are frequently cited in glaucoma-related experimental models.
Q5: How should Carbachol be stored?
Carbachol is hygroscopic and should be stored in airtight containers, protected from light and moisture, to maintain stability during long-term storage.
Q1. How can I request a quotation or sample?
You can click the “Send Inquiry” button on this page or email us directly at [email protected].
Samples are available for most products, and our sales team will reply within 24 hours with detailed pricing and documentation .
Q2. What is the minimum order quantity (MOQ)?
The MOQ is 0.5 kg for most products.
For laboratory evaluation or small trial batches, smaller quantities can be arranged depending on stock availability.
Q3. What certifications do your products comply with?
Our GMP-certified partners operate under ISO, CEP, and FSC standards.
Each batch is supplied with a full set of COA, MSDS, and export documents to ensure quality traceability.
Q4. How long does delivery take?
Usually 3–7 working days for available stock and 2–3 weeks for customized specifications or large orders.
Q5. Which payment methods do you accept?
We accept T/T, L/C, and other agreed terms depending on the order volume and region.
Q6. Can you provide contract manufacturing or custom formulation support?
Yes. We cooperate with multiple GMP facilities to offer custom synthesis, formulation, and registration support for specific markets.
Packaging Information
Standard packing: 25 kg fiber drum or 1 kg foil bag
Double PE inner liner for moisture protection
Custom packaging available on request
Storage & Stability
Store in a cool, dry environment away from direct light. Shelf life 24 months under recommended conditions.
Transportation
Shipped by air, sea, or express according to customer preference. Dangerous goods comply with IATA/IMDG standards if applicable.
Our company and partner facilities hold valid GMP and ISO certificates issued by national authorities, ensuring that every batch meets strict quality and traceability standards required for international veterinary API markets.
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