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Ceftiofur Hydrochloride Injection 5%
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Overview
Ceftiofur Hydrochloride Injection 5% is a third-generation cephalosporin antibiotic formulation for veterinary use. Each milliliter contains 50 mg of Ceftiofur Hydrochloride in an oil-based suspension, designed for sustained antibacterial effect and reduced injection frequency.
It provides broad-spectrum activity against Gram-positive and Gram-negative bacteria, including Pasteurella multocida, Actinobacillus pleuropneumoniae, Salmonella spp., and Streptococcus spp.. The product is mainly indicated for respiratory infections, foot rot, metritis, and bacterial pneumonia in cattle and swine.
Product Information
This formulation ensures rapid absorption and prolonged plasma concentration, providing effective antibacterial activity with a single daily injection. It reduces handling stress for animals and is well tolerated in various livestock species.
Pharmacological Action
Ceftiofur, a β-lactam antibiotic, inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins. It is resistant to most β-lactamases, maintaining efficacy against a wide range of respiratory and systemic pathogens in livestock.
Composition
- Active ingredient: Ceftiofur Hydrochloride 50 mg/mL
- Base: Oil suspension for slow release
- Appearance: Light yellow to brownish-yellow liquid
- Type: Injectable suspension (veterinary use only)
Advantages
- Broad-spectrum antibacterial activity against key respiratory and systemic pathogens
- Oil-based formulation ensures longer therapeutic effect
- Low tissue irritation and minimal injection site reaction
- Effective once-daily dosing for convenience and compliance
Technical Specifications
| Item | Specification |
|---|---|
| Active Ingredient | Ceftiofur Hydrochloride 50 mg/mL |
| Formulation | Sterile oil suspension |
| Appearance | Light yellow to brownish-yellow liquid |
| pH Range | 6.0 – 8.0 |
| Assay | 95% – 105% of label claim |
| Sterility | Complies with USP/EP standards |
| Shelf Life | 24 months under 25°C |
Each batch is tested for sterility, viscosity, and assay consistency in GMP-certified facilities.
Quality Assurance
All production and quality control of Ceftiofur Hydrochloride Injection 5% are performed under GMP and ISO-certified standards. The product is validated for potency, purity, and stability to ensure consistent efficacy and safety.
- Manufactured under GMP & ISO 9001:2015 systems
- Batch documentation: COA, MSDS, and Certificate of Origin
- Packaging: 50 mL, 100 mL, and 250 mL sterile glass vials
Storage: Store below 25°C, away from light and freezing.
Shelf Life: 24 months in sealed packaging.
Applications & Dosage
Indicated for the treatment of bacterial infections caused by Pasteurella, Actinobacillus, and Streptococcus in cattle, pigs, and sheep. Particularly effective against respiratory infections, metritis, and foot rot.
Recommended Dosage
- Cattle: 1 mL per 20 kg body weight, once daily for 3–5 days
- Swine: 1 mL per 16 kg body weight, once daily for 3 days
- Sheep: 1 mL per 25 kg body weight, once daily for 3–5 days
Administer intramuscularly or subcutaneously. Shake well before use. Do not inject more than 10 mL per site. Use sterile equipment and proper injection technique.
Product FAQ
Q1: What is Ceftiofur Hydrochloride Injection 5% used for?
A: It treats bacterial infections such as pneumonia, metritis, and foot rot in cattle and swine caused by susceptible organisms.
Q2: How does Ceftiofur Hydrochloride work?
A: It inhibits bacterial cell wall synthesis and is stable to most β-lactamases, maintaining strong antibacterial effect.
Q3: What is the withdrawal period?
A: Meat: 4 days after the last treatment. Milk: Not for use in lactating animals producing milk for human consumption.
Q4: Can it be mixed with other antibiotics?
A: Do not mix with aminoglycosides or tetracyclines in the same syringe to prevent incompatibility.
Q5: How should it be stored?
A: Store below 25°C, avoid light and freezing. Shake well before use.
Q6: Is it safe for pregnant animals?
A: Generally safe when used under veterinary supervision. Avoid excessive dosage during late pregnancy.
Q1. How can I request a quotation or sample?
You can click the “Send Inquiry” button on this page or email us directly at [email protected].
Samples are available for most products, and our sales team will reply within 24 hours with detailed pricing and documentation .
Q2. What is the minimum order quantity (MOQ)?
The MOQ is 0.5 kg for most products.
For laboratory evaluation or small trial batches, smaller quantities can be arranged depending on stock availability.
Q3. What certifications do your products comply with?
Our GMP-certified partners operate under ISO, CEP, and FSC standards.
Each batch is supplied with a full set of COA, MSDS, and export documents to ensure quality traceability.
Q4. How long does delivery take?
Usually 3–7 working days for available stock and 2–3 weeks for customized specifications or large orders.
Q5. Which payment methods do you accept?
We accept T/T, L/C, and other agreed terms depending on the order volume and region.
Q6. Can you provide contract manufacturing or custom formulation support?
Yes. We cooperate with multiple GMP facilities to offer custom synthesis, formulation, and registration support for specific markets.
Packaging Information
Standard packing: 25 kg fiber drum or 1 kg foil bag
Double PE inner liner for moisture protection
Custom packaging available on request
Storage & Stability
Store in a cool, dry environment away from direct light. Shelf life 24 months under recommended conditions.
Transportation
Shipped by air, sea, or express according to customer preference. Dangerous goods comply with IATA/IMDG standards if applicable.
Our company and partner facilities hold valid GMP and ISO certificates issued by national authorities, ensuring that every batch meets strict quality and traceability standards required for international veterinary API markets.
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