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Florfenicol
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Overview
Florfenicol is a synthetic broad-spectrum veterinary antibiotic belonging to the amphenicol class. It is widely used to treat respiratory, gastrointestinal, and systemic bacterial infections in cattle, swine, poultry, and aquatic species. Compared with chloramphenicol and thiamphenicol, Florfenicol offers enhanced antibacterial activity and improved safety due to the absence of the nitro group.
Its excellent tissue distribution and longer half-life provide reliable therapeutic outcomes in intensive livestock production.
Product Information
Active Ingredient: Florfenicol
Grade: Veterinary Grade (CVP 2020 compliant)
Dosage Form (Usage): API for premix, oral solution, injectable preparations
Mode of Action: Florfenicol inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit, producing bacteriostatic activity.
Spectrum: Effective against *Pasteurella*, *Actinobacillus*, *Streptococcus*, *Mycoplasma*, *E. coli* and other Gram-negative and Gram-positive pathogens.
Target Species: Swine, cattle, poultry, fish, and other livestock
Regulatory Compliance: Conforms to CVP 2020 and in-house specifications.
Technical Specifications
| Appearance | White to almost white crystalline powder |
| Melting Point | 152.0–156.0°C |
| Optical Rotation | -16° to -19° |
| pH | 4.5–6.5 (COA result: 6.0) |
| Chloride | ≤0.02% |
| Fluorine | ≥4.8% |
| Single Impurity | ≤0.5% (COA: 0.2%) |
| Total Impurities | ≤2.0% (COA: 0.38%) |
| Water | ≤0.5% (COA: 0.1%) |
| Residue on Ignition | ≤0.1% (COA: 0.05%) |
| Heavy Metals | ≤20 ppm |
| Assay | ≥98.0% (COA: 99.0%) |
All data are based on the provided COA and CVP 2020 standard.
Quality Assurance
Our Florfenicol is manufactured in GMP-compliant facilities with strict in-house and CVP 2020 quality controls. Each batch undergoes testing for assay, impurities, physical characteristics, and safety parameters including heavy metals and solvent residues.
We provide full regulatory support:
• COA (batch-specific)
• MSDS
• GMP certificates
• Stability data (if required)
• Export documentation for global markets
All shipments are sealed in airtight containers to prevent moisture and ensure long-term stability.
Reference: European Pharmacopoeia veterinary antimicrobial standards.
Applications & Dosage
Applications:
• Treatment of bovine respiratory disease (BRD)
• Control of swine respiratory disease caused by *Actinobacillus pleuropneumoniae* and *Pasteurella multocida*
• Prevention and treatment of bacterial infections in poultry
• Widely used in aquaculture for systemic bacterial diseases
Common Dosage Reference (for finished products):
• Swine: 20–30 mg/kg body weight per day for 3–5 days
• Cattle (injectable preparations): 20 mg/kg as a single dose or divided doses
• Poultry: 30 mg/kg via drinking water
• Aquaculture: 10–15 mg/kg feed for 5–7 days
Note: Above dosages refer to finished dosage forms, not API. Follow local regulations and veterinarian instructions.
Product FAQ
1. What is the difference between Florfenicol and Chloramphenicol?
Florfenicol has no nitro group, making it safer and legally acceptable for veterinary use, with stronger antibacterial activity.
2. Can Florfenicol be used in aquatic species?
Yes. It is commonly used in fish and shrimp feed to control systemic bacterial infections.
3. What is the shelf life?
24 months when stored in airtight containers away from heat and moisture.
4. Does Florfenicol dissolve in water?
It is practically insoluble in water but highly soluble in DMF and methanol.
5. Do you provide documents for registration?
Yes — COA, MSDS, process flow, impurity profile, and other regulatory documents can be supplied.
Q1. How can I request a quotation or sample?
You can click the “Send Inquiry” button on this page or email us directly at [email protected].
Samples are available for most products, and our sales team will reply within 24 hours with detailed pricing and documentation .
Q2. What is the minimum order quantity (MOQ)?
The MOQ is 0.5 kg for most products.
For laboratory evaluation or small trial batches, smaller quantities can be arranged depending on stock availability.
Q3. What certifications do your products comply with?
Our GMP-certified partners operate under ISO, CEP, and FSC standards.
Each batch is supplied with a full set of COA, MSDS, and export documents to ensure quality traceability.
Q4. How long does delivery take?
Usually 3–7 working days for available stock and 2–3 weeks for customized specifications or large orders.
Q5. Which payment methods do you accept?
We accept T/T, L/C, and other agreed terms depending on the order volume and region.
Q6. Can you provide contract manufacturing or custom formulation support?
Yes. We cooperate with multiple GMP facilities to offer custom synthesis, formulation, and registration support for specific markets.
Packaging Information
Standard packing: 25 kg fiber drum or 1 kg foil bag
Double PE inner liner for moisture protection
Custom packaging available on request
Storage & Stability
Store in a cool, dry environment away from direct light. Shelf life 24 months under recommended conditions.
Transportation
Shipped by air, sea, or express according to customer preference. Dangerous goods comply with IATA/IMDG standards if applicable.
Our company and partner facilities hold valid GMP and ISO certificates issued by national authorities, ensuring that every batch meets strict quality and traceability standards required for international veterinary API markets.
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