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Milbemycin Oxime
CAS No.
Appearance
Purity
Molecular Formula
Molecular Weight
Solubility
Synonyms
Table of Contents
Overview
Milbemycin Oxime (CAS 129496-10-2) is a macrocyclic lactone–class veterinary API widely used by pharmaceutical manufacturers to formulate antiparasitic products for companion animals and livestock. It is derived from naturally occurring milbemycins and supplied as a white to off-white crystalline powder with stable physical and chemical properties.
Thanks to its well-defined impurity profile and compatibility with solid and semi-solid manufacturing processes, Milbemycin Oxime is commonly selected for tablets, chewable formulations and combination products in the veterinary pharmaceutical industry.
Product Information
| Product Name | Milbemycin Oxime |
| CAS No. | 129496-10-2 |
| Chemical Formula | C32H45NO7 |
| Molecular Weight | 555.71 g/mol |
| Appearance | White to off-white powder |
| Purity (HPLC) | Not less than 95.0% |
| Solubility | Practically insoluble in water; soluble in ethanol, methanol and acetone |
| Melting Behavior | Shows characteristic melting range for macrocyclic lactones |
| Identification | Conforms to reference IR spectrum and HPLC retention time |
| Heavy Metals | ≤10 ppm |
| Loss on Drying | ≤3.0% |
| Residue on Ignition | ≤0.2% |
| Related Substances | Total impurities ≤3.5%; individual ≤0.5% |
| Residual Solvents | Controlled according to internal limits |
| Microbial Quality | Meets internal requirements for API-grade materials |
| Particle Size | D(0.9) ≤ 50 μm; D(0.5) ≤ 3 μm (typical) |
| Packaging | 1 kg foil bag or 25 kg fiber drum; customizable |
| Storage | Store in a dry, sealed container away from light |
| Shelf Life | 24 months under recommended conditions |
| Form | Powder |
| Color | White to off-white |
| Purity | ≥95.0% (HPLC) |
| Impurities | Total ≤3.5% |
| Loss on Drying | ≤3.0% |
| Residue on Ignition | ≤0.2% |
| Heavy Metals | ≤10 ppm |
| Particle Size | D(0.9) ≤ 50 μm; D(0.5) ≤ 3 μm |
| Solvent Residues | Controlled per internal standards |
| Microbial Quality | Meets internal API limits |
Quality Assurance
Milbemycin Oxime is supplied through qualified manufacturing partners with stable quality control systems. Each batch is tested for identity, assay and impurities according to internal specifications before release. Packaging and palletizing can be arranged according to customer requirements, and evaluation samples are available upon request.
Technical Specifications
| Form | Powder |
| Color | White to off-white |
| Purity | ≥95.0% (HPLC) |
| Impurities | Total ≤3.5% |
| Loss on Drying | ≤3.0% |
| Residue on Ignition | ≤0.2% |
| Heavy Metals | ≤10 ppm |
| Particle Size | D(0.9) ≤ 50 μm; D(0.5) ≤ 3 μm |
| Solvent Residues | Controlled per internal standards |
| Microbial Quality | Meets internal API limits |
Product FAQ
What is Milbemycin Oxime used for in the veterinary pharmaceutical industry?
It serves as an active raw material for producing broad-spectrum antiparasitic formulations, especially solid-dose products for companion animals.
Why is Milbemycin Oxime often combined with other APIs?
Manufacturers may combine it with complementary ingredients to expand product application range and improve formulation flexibility.
What makes Milbemycin Oxime suitable for tablet and chewable formulation?
Its stable powder characteristics, defined particle-size distribution and good blending behavior support efficient granulation and compression.
Is Milbemycin Oxime water-soluble?
It is practically insoluble in water, so it is mainly used in solid or semi-solid dosage designs rather than aqueous systems.
What information helps when requesting a quotation?
Required quantity, packaging preference, target market and special specifications such as particle size or impurity limits help us prepare an accurate offer.
Q1. How can I request a quotation or sample?
You can click the “Send Inquiry” button on this page or email us directly at [email protected].
Samples are available for most products, and our sales team will reply within 24 hours with detailed pricing and documentation .
Q2. What is the minimum order quantity (MOQ)?
The MOQ is 0.5 kg for most products.
For laboratory evaluation or small trial batches, smaller quantities can be arranged depending on stock availability.
Q3. What certifications do your products comply with?
Our GMP-certified partners operate under ISO, CEP, and FSC standards.
Each batch is supplied with a full set of COA, MSDS, and export documents to ensure quality traceability.
Q4. How long does delivery take?
Usually 3–7 working days for available stock and 2–3 weeks for customized specifications or large orders.
Q5. Which payment methods do you accept?
We accept T/T, L/C, and other agreed terms depending on the order volume and region.
Q6. Can you provide contract manufacturing or custom formulation support?
Yes. We cooperate with multiple GMP facilities to offer custom synthesis, formulation, and registration support for specific markets.
Packaging Information
Standard packing: 25 kg fiber drum or 1 kg foil bag
Double PE inner liner for moisture protection
Custom packaging available on request
Storage & Stability
Store in a cool, dry environment away from direct light. Shelf life 24 months under recommended conditions.
Transportation
Shipped by air, sea, or express according to customer preference. Dangerous goods comply with IATA/IMDG standards if applicable.
Our company and partner facilities hold valid GMP and ISO certificates issued by national authorities, ensuring that every batch meets strict quality and traceability standards required for international veterinary API markets.
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